ANA4 - Antinuclear antibodies (ANA) (+ titer), ANA/ENA by Immunoblot
The test is performed as part of an in-depth and detailed diagnosis of autoimmune diseases, assessing (qualitative + semi-quantitative) the presence of antibodies for conditions such as systemic lupus erythematosus (SLE), Sjogren's syndrome, mixed connective tissue disease (Sharp syndrome, MCTD), systemic sclerosis (SSc), limited scleroderma (LoSc), polymyositis (PM), dermatomyositis (DM), overlap syndrome, CREST syndrome/scleroderma, and type I autoimmune hepatitis (AIH).

ClinicLab
- Test description
The ANA4 test detects antinuclear antibodies (ANA) and provides a detailed analysis of their types using the immunoblot method (ANA/ENA IB). It is used for diagnosing autoimmune diseases, such as lupus or Sjogren's syndrome, helping identify specific proteins targeted by these antibodies.
When to perform the test?
The test is performed on patients to provide a detailed analysis of antinuclear and cytoplasmic antibodies, which enables differential diagnosis of autoimmune diseases. This test supports monitoring disease activity, the therapeutic process, as well as predicting future disease occurrence.
Conditions:
ANA4 - Antinuclear Antibodies ANA (+ titer), ANA/ENA IB by immunoblot method are measured in detailed diagnostics of autoimmune diseases, such as systemic lupus erythematosus (SLE), Sjogren's syndrome, mixed connective tissue disease (Sharp syndrome, MCTD), systemic sclerosis (SSc), limited scleroderma (LoSc), polymyositis (PM), dermatomyositis (DM), overlap syndrome, CREST syndrome/scleroderma, type I autoimmune hepatitis (AIH), and primary biliary cirrhosis (PBC).