Anti-insulin antibodies (Anti-IAA)

Antibodies against insulin are tested in patients with prediabetes and for the diagnosis of Type 1 diabetes (T1DM) and LADA (Latent Autoimmune Diabetes in Adults).

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Test description

Insulin antibodies (Anti-IAA) are proteins produced in the body that attack insulin, the hormone regulating blood sugar levels. Their presence is particularly associated with Type 1 diabetes, where the immune system mistakenly identifies insulin as a threat, which can lead to issues with glucose control. Testing for these antibodies aids in the diagnosis of diabetes.

When to perform the test?

The test is performed on children over the age of 5 (who exhibit the highest titers) and on individuals genetically predisposed to developing T1DM. Their characteristic presence is also observed in prediabetic patients.

Conditions:

Insulin antibodies (Anti-IAA) are measured in the diagnosis of conditions such as Type 1 diabetes (T1DM) and LADA diabetes.

Symptoms:

The Anti-IAA antibody test is performed when symptoms such as increased thirst (polydipsia), frequent urination (polyuria), reduced skin elasticity, weakness and drowsiness, a tendency for urinary tract infections, altered consciousness, ketoacidosis, and diabetic coma are observed.