Anti-native DNA antibodies (Anti-nDNA, Crithidia luciliae)

The native DNA (Anti-nDNA) antibody test detects antibodies directed against cell DNA. It is particularly used in diagnosing systemic lupus erythematosus (SLE), with the Crithidia luciliae method aiding in accurately assessing the presence of these antibodies.

When to Perform the Test?

This test is conducted as part of the diagnostic process for patients with systemic lupus erythematosus and for monitoring the effects of immunosuppressive therapy. Anti-dsDNA is the most specific serological marker for SLE, aiding in differentiating SLE from systemic sclerosis (SSc).

Diseases

Native DNA antibodies (Anti-nDNA, Crithidia luciliae) are measured for diagnosing conditions such as systemic lupus erythematosus (SLE) and neonatal lupus.

Symptoms

The Anti-nDNA test is conducted after observing symptoms such as fatigue, malaise, low-grade fever, joint pain (often in wrists, fingers, knees, and feet) with swelling, migratory muscle pain with