Antibodies against neutrophils by immunofluorescence (ANCA - F)
The test is performed in the diagnosis of diseases involving vasculitis (e.g., Wegener's granulomatosis, eosinophilic granulomatosis with polyangiitis, microscopic polyangiitis); chronic diseases of the kidneys, liver, lungs, colon, and toxin poisoning. Antibodies against neutrophil granulocytes are measured.

ClinicLab
- Test description
The anti-neutrophil cytoplasmic antibody (ANCA) test by immunofluorescence (ANCA-F) detects antibodies that attack these blood cells. The test is performed in the diagnosis of diseases involving vasculitis (e.g., Wegener's granulomatosis, eosinophilic granulomatosis with polyangiitis, microscopic polyangiitis); in chronic diseases of the kidneys, liver, lungs, colon, and in cases of toxin poisoning.
When to Perform the Test?
This test is recommended as a first-line test in the presence of symptoms of vascular autoimmune disease.
Associated Conditions
Anti-neutrophil cytoplasmic antibodies (ANCA) by immunofluorescence (ANCA-F) are measured in the diagnosis of conditions such as diseases involving vasculitis (e.g., Wegener's granulomatosis, eosinophilic granulomatosis with polyangiitis, microscopic polyangiitis), chronic diseases of the kidneys, liver, lungs, colon, and toxin poisoning.
Symptoms
The anti-neutrophil cytoplasmic antibody (ANCA) test by immunofluorescence (ANCA-F) is performed after observing symptoms such as cough, hemoptysis, nosebleeds, shortness of breath, chest pain, and recurring respiratory infections.