Test of genetic predispositions to the development of Alzheimer's disease - 4 genes

Genetic Testing for Alzheimer’s Disease – Test Description

The panel includes 4 genes: APOE, APP, PSEN1, PSEN2. The test is performed using Next Generation Sequencing (NGS) technology. This technology enables highly accurate examination of all regions within these genes in your DNA that may contain potentially pathogenic variants (mutations), which could contribute to the development of Alzheimer's disease in the future.

Genetic Testing for Alzheimer's Disease – Indications

Genetic testing for Alzheimer’s is recommended for:

• Individuals with family members who have had this disease;

• Individuals who have symptoms that may indicate early onset of the disease.

Alzheimer’s Test – Preparation for the Test

The test requires no special preparation. There is no need to fast before the blood/material sample is taken. The genetic test for Alzheimer’s can be done at one of the Damian Medical Center locations. A full list of available locations is shown above the test description in the shopping section—first select your city of interest and then the most convenient location for you.

Within 48 hours (on business days) after purchasing the Alzheimer's test panel, one of our medical staff members will contact you to conduct a medical interview.

Genetic Testing for Alzheimer's – Results

The wait time for the result is a maximum of 30 business days. The result will be sent to the email address provided during the medical interview and to the referring physician.

For individuals with a positive test result, there is an option to purchase consultations with a geneticist and a psychologist for 1 PLN each. The purchase is only available at Damian Medical Center locations.

Alzheimer’s Diagnostics – Testing Technology

The genetic panels we offer are performed using Next Generation Sequencing (NGS), ensuring both high sensitivity and specificity of the test, and the report we provide stands out in quality and accuracy.

NGS technology enables in-depth analysis of the entire coding DNA sequence and key non-coding sequence fragments in the tested genes. These areas may contain pathogenic changes (variants) associated with the risk of developing serious diseases, including cancer. Unlike popular genetic tests, such as PCR tests, which focus on analyzing only a few of the most common mutations, our panels cover the full spectrum of potential changes. This broad analysis allows for the detection of even rarer variants that may go unnoticed in standard tests but could be crucial in assessing the risk of developing Alzheimer's or other conditions.

NGS sequencing, supported by advanced data analysis algorithms, achieves a sensitivity level of 99.93% in detecting individual nucleotides in our genetic panels. This high detection standard places our genetic panels among the top tests available in the Polish market, offering one of the most advanced methods of health prediction.

Genetic Test for Alzheimer's – Price

The cost of this test at Damian Medical Center in Warsaw is 2250 PLN.

Who do we inherit Alzheimer’s from?

Although genes from both parents can influence the predisposition to Alzheimer’s, inheritance from the mother is a significant risk factor, as demonstrated in numerous scientific studies.

Is it possible to do genetic testing for Alzheimer’s?

Yes, genetic testing for Alzheimer’s disease can be done, including at Damian Medical Center locations.

How much does the Alzheimer’s test cost?

The cost of genetic testing for Alzheimer’s disease can vary depending on the scope of the analysis and the selected medical facility. At Damian Medical Center in Warsaw, the cost of such a test is 2250 PLN.

How to take the Alzheimer’s test?

To perform a genetic test for Alzheimer’s disease, you need to visit a medical facility offering such testing, such as Damian Medical Center. The process usually starts with a consultation with a doctor or geneticist, who will explain the test and which genes will be analyzed. Then, a blood or saliva sample is taken, which is analyzed in a laboratory using Next Generation Sequencing (NGS) technology.