Borrelia burgdorferi DNA

The purpose of the test is to detect the presence of genetic material (DNA) of Borrelia burgdorferi by PCR. The PCR test shows high sensitivity and specificity. The Real-time PCR technique makes it possible to detect the presence of bacterial DNA in the early stages of infection before the development of an immune response. Serologic tests should be performed approximately 4 weeks after the bite.

Clinical significance:

Borrelia burgdorferi is the spirochete that causes Lyme disease (Lyme disease). The vector that transmits the spirochete is ticks.

Lyme disease is a multisystem disease, in the course of which it is possible to distinguish successive stages of development resulting in the involvement of various systems and the occurrence of complications. An early sign of infection is the so-called erythema migrans. Real-time PCR technique makes it possible to detect the presence of bacterial DNA in the early stages of infection before the development of an immune response. It is most advisable to perform the test up to three weeks after a tick bite, before bacteria from the bloodstream enter the tissues.

Indications for the test: individuals suspected of being infected with Borrelia burgorferi (especially in the early stages of infection).