Phenytoin

Phenytoin - an antiepileptic and antiarrhythmic drug. It acts stabilizes the cell membrane of neurons by modifying the ion flow causes an increase in the seizure threshold. During action potential, it inhibits the intracellular sodium current, during the depolarization phase reduces the influx of calcium ions into the cell Inhibits the motor cortex and subcortical centers responsible for the tonic phase of convulsions. Phenytoin weakens the force of myocardial contraction and also affects myocardial impulse conduction. Determination of Used in suspected drug overdose.