IgG antibodies against VZV (Varicella zoster virus - Chickenpox, Shingles)

The Varicella-Zoster Virus (VZV) IgG test detects antibodies indicating a past infection with chickenpox or shingles, as well as acquired immunity.

When to Perform the Test

The test is useful in diagnosing primary VZV infection as well as reactivation of the infection. A temporary increase in IgG antibody levels indicates an appropriate immune response, and their presence is useful in assessing the post-vaccination response.

Medical Conditions

Chickenpox and shingles.

Symptoms

In children, symptoms may include rash. In adults, symptoms may include pneumonia, meningitis, encephalitis, myocarditis, secondary bacterial complications (staphylococcal and streptococcal infections), severe irritation and skin changes in the affected nerve area, as well as intense pain and itching at the site of nerve involvement.