Thiopurine methyltransferase
Thiopurine methyltransferase (TPMT) is an enzyme involved in the metabolism of someós immunosuppressive drugs and those used in the treatment of inflammatory bowel diseases.

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Thiopurine methyltransferase
Clinical relevance
Thiopurine methyltransferase (TPMT) is an enzyme involved in the metabolism of someów immunosuppressive drugs and those used to treat inflammatory bowel disease. Determination of low or no TPMT activity before starting azathioprine or mercaptopurine treatment is helpful in avoiding life-threatening drug complications.
Patient Preparation
Material: Blood EDTA