TOXO (Toxoplasmosis) IgG antibodies

Specific IgG antibodies produced by the body in response to contact with the parasite Toxoplasma gondii (a protozoan), which causes toxoplasmosis. Infection with this parasite can occur through:

Consumption of raw or undercooked meat contaminated with the parasite (particularly pork, lamb, or game meat) or contaminated fruits and vegetables that have come into contact with parasite oocysts present in soil.

Another route of infection is contact with contaminated cat feces, as cats are the primary hosts of the parasite. Infection may occur, for example, when cleaning a litter box without appropriate protective measures.

The presence of IgG antibodies, with a negative IgM result, indicates a past infection (latent phase), which does not require treatment in individuals with normal immunity.

When to Perform the Test

This test is recommended as a preventive measure for women planning pregnancy or already pregnant, as the presence of isolated IgG antibodies in pregnant women provides protection against primary infection during pregnancy.

Medical Conditions

The parasite Toxoplasma gondii causes toxoplasmosis.

Symptoms

Toxoplasmosis may present with symptoms such as low-grade fever or fever, joint and muscle pain, general malaise and weakness, skin changes (rashes), lymphadenopathy. In newborns, symptoms may include retinal and brain lesions, encephalitis, microcephaly, hydrocephalus, cerebral palsy, delayed psychomotor development, and epilepsy.