Urogenital 4
Identification of DNA of 4 urogenital tract pathogens.
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Identification of DNA from 4 urogenital pathogens:
- Chlamydia trachomatis
- Ureaplasma spp.
- Mycoplasma genitalium
- Mycoplasma hominis
Benefits of the test:
Early identification of the cause of urogenital infection results in faster implementation of appropriate treatment, which can protect the patient from unpleasant consequences of its progression.
Indications for performing the Urogenital 4 test:
For women:
• Sexual activity with a history of contact with infected partners • Symptoms of urogenital tract infection • Pregnancy or planning to expand the family
For men:
• Sexual activity with a history of contact with infected partners • Symptoms of urogenital tract infection
Ureaplasma parvum and Ureaplasma urealyticum
In women, the presence of these bacteria can cause inflammation of the ovaries, fallopian tubes, or cervix. In men, untreated infection may be associated with fertility problems, prostatitis, epididymitis, or kidney inflammation. Infection with these bacteria can also occur through transplacental transmission and during childbirth. A serious complication of untreated Ureaplasma urealyticum infection in pregnant women is inflammation of the fetal membranes and placenta, which can lead to premature birth.
Chlamydia trachomatis
An intracellular Gram-negative bacterium. Bacterial infections with Chlamydia trachomatis are mainly associated with inflammation of the urogenital tract. In women, it can lead to urethritis, cervicitis, and pelvic inflammatory disease. In men, infection results in epididymitis and orchitis. A characteristic feature of the bacterium is its ability to persist in host cells, leading to latent or chronic infections. In most cases, Chlamydia trachomatis infection is asymptomatic. Untreated chlamydia leads to complications: For women: the formation of adhesions between the fallopian tubes and ovaries, mechanical infertility, and pregnancy complications (miscarriages, ectopic pregnancies) For men: partial or complete obstruction of the epididymal and vas deferens ducts, leading to mechanical infertility. For newborns: perinatal transmission can cause conjunctivitis and eye infections.
Mycoplasma hominis and Mycoplasma genitalium
These bacteria can exhibit pathogenic properties and cause urogenital tract infections, including urethritis in men and inflammation of the ovaries and fallopian tubes in women. The infection can lead to a decrease in sperm count and motility, as well as structural abnormalities in sperm. Untreated Mycoplasma hominis and Mycoplasma genitalium infections can result in infertility in both women and men. Mycoplasma hominis and Mycoplasma genitalium bacteria lack a cell wall, which makes them naturally resistant to commonly used beta-lactam antibiotics. The course of infection may be asymptomatic or present with mild clinical symptoms.