Anti-tyrosine phosphatase antibodies (Anti-IA2)
Highly specific antibodies against tyrosine phosphatase are tested as a complementary examination alongside anti-GAD antibodies. This test aids in diagnosing LADA (Latent Autoimmune Diabetes in Adults) or identifying individuals genetically predisposed to developing Type 1 Diabetes (T1DM).

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- Test description
The antibody test for tyrosine phosphatase (Anti-IA2) is used in the diagnosis of Type 1 diabetes. The presence of these antibodies indicates an immune system attack on pancreatic cells, leading to insulin deficiency.
When to perform the test?
This test is performed for patients in the diagnosis of Type 1 diabetes, as a complementary test alongside anti-GAD antibodies, useful in diagnosing LADA (Latent Autoimmune Diabetes in Adults) and for individuals genetically predisposed to developing T1DM.
Conditions:
Tyrosine phosphatase antibodies (Anti-IA2) are measured in the diagnosis of conditions such as Type 1 diabetes (T1DM) and LADA diabetes.
Symptoms:
The Anti-IA2 antibody test is performed when symptoms such as increased thirst (polydipsia), frequent urination (polyuria), reduced skin elasticity, weakness and drowsiness, a tendency for urinary tract infections, altered consciousness, ketoacidosis, and diabetic coma are observed.