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Anti-granulocytic ANCA antibodies, glow type

AnCA granulocyte anti-cytoplasmic antibodies are present in many immunologic diseases, such as Wegener's granulomatosis, rheumatoid arthritis, and can also occur in healthy individuals individuals.

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  • Test description
Test description

Anti-cytoplasmic granulocyte antibodies ANCA are autoantibodies mainly of the IgG class that react with components of granules found on granulocytes. ANCAs are present in many diseases immunological diseases such as Wegener's granulomatosis, rheumatoid arthritis, and can also occur in healthy individuals. ANCAS, which are detected by indirect immunofluorescence (the method with the highest sensitivity), are divided into c - ANCA (cytoplasmic) showing fluorescence of the entire cytoplasm, this type of fluorescence show mainly antibodies against proteinase 3; p-ANCA (perinuclear) showing fluorescence around the nucleus, this type is shown by antibodies directed against myeloperoxidase (MPO).