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Plasma free hemoglobin

Slow plasma hemoglobin is a blood test that&oac;re measures the level of a protein called hemoglobin released from red blood cells into the liquid part of the blood (plasma). This test is used to assess hemolysis, the breakdown of red blood cells.

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Test description

Free hemoglobin in plasma

Clinical significance

Free hemoglobin appears in plasma when it is released from red blood cells (erythrocytesów), and the possibility of its uptake and transport by haptoglobin has been exhausted. Determination of free hemoglobin is used to diagnose hemolytic syndromes, in whichór there is an increased breakdown of erythrocytesów and thus large amounts of hemoglobin are released. In addition, free hemoglobin binds to nitric oxide (NO), whichós vasodilatory and blood pressure-regulating effects. This reaction irreversibly produces methemoglobin. A relatively small amount of free hemoglobin can lead to complete binding of NO and dysfunction of the mediastinum as well as thrombotic disorders.

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Material: Plasma

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