Assessment of the genetic predispositions to thrombosis: mutations of the prothrombin gene (factor II) and Leiden (factor V)

Genetic thrombosis test - convenient to perform, quick result

This test will allow you to quickly know your risk of developing thrombosis resulting from a genetic condition. Its purpose is to testing your genotype for Leiden mutations in the factor V gene and mutations in the factor II (prothrombin) gene. Mutations in these genes increase the risk of thrombosis by several times.

Doing the test will allow you to apply appropriate prophylaxis and, if necessary, start early treatment.

The risk of thrombosis is increased by a few factors

Main benefits of getting a thrombosis test:

• easy and convenient testing without leaving home
• the result is sent within 14 working days in the form of a paper through the Polish Post Office or electronically
• the result is sent to you in the form of a paper electronically
• You will receive the saliva sample self-sampling kit within 5 business days
• security and confidentiality of data
• guarantee of the highest quality standards of the test- service implemented by Nucleagen Laboratory, which has several years of experience in genetic testing, QCMD and INSTAND quality certificates.

For whom is genetic testing for predisposition to thrombosis?

In the increased risk group are people who:

• are taking oral contraceptives,
• are pregnant or planning a pregnancy,
• have an aggravating family history (occurrence of thrombosis in the family), such as repeated episodes of thrombosis in a close relative before the age of 50 years,
• have a history of thrombosis episodes, suffer from varicose veins or lead a sedentary lifestyle.

Persons in the risk group should conduct a genetic testing.

Genetic test material collection

The test is performed from a saliva sample taken as a swab from the buccal mucosa. It is necessary to read the instructions attached to the collection kit and carefully perform each point described therein point. The result of the test depends primarily on the quality and quantity of DNA in the collected material. Following the recommendations the attached instructions should ensure a correct result.

Information about the test

Aims and limitations of the study

The purpose of the test is to find genetic changes that may be responsible for the onset of a specific disease. Failure to find a genetic change genetic change does not mean that the disease cannot occur The likelihood of thrombosis is increased by: taking oral contraception, a sedentary lifestyle and an unhealthy diet.

Interpretation of a genetic test result depends on current medical knowledge, as well as a number of environmental and family conditions and family circumstances. Incomplete medical information regarding the patient or his or her family, including a different than declared relationship between the members of the family under study, can result in the results obtained tests will be misinterpreted.

Further medical decisions regarding the planned therapy, herein methods of disease prevention, should be based on a comprehensive assessment of the patient's health situation patient's health situation, and the obtained results of the genetic test supporting the decision-making process

Sampling

Genetic analysis is performed on the basis of a buccal swab buccal swab. Its results depend primarily on the quality and quantity of DNA in the collected material. It is necessary to strictly follow the rules of collection and follow the instructions included in the collection kit collection kit.

Notwithstanding adherence to laboratory standards, isolated material may not be in sufficient quantity or may undergo degraded (destroyed), making it impossible to perform the ordered genetic analysis. In such a case, it may be necessary to re-collection of material (swab from the mucous membrane of the inner side of the cheek). In such a situation, please contact Customer Customer Service, and we will send an additional collection kit free of charge.

How to collect the material for testing?

Check how to collect the material for genetic testing. . In our instructions you will find the exact steps to follow when collecting the material and a video tutorial.

The result of the test is sent directly to the address indicated by the patient. It does not include medical consultation in Medicover Centres or its interpretation. In case of a result confirming the predisposition to the development of thrombophilia, the result should be consulted with your attending physician.

Information on the examination

Objectives and limitations of the test

The objective of the test is to find genetic modifications that may be responsible for the occurrence of a specific disease. Failure to find a genetic mutations does not mean that the disease will never occur. The probability of thrombosis development is increased by oral contraception, sedentary lifestyle and an unhealthy diet.

The interpretation of a genetic test result depends on current medical knowledge as well as a number of environmental and family factors. Incomplete medical information about the patient or patient's family, including any other kinship than declared between any members of the family, may result in misinterpretation of the test results.

Further medical decisions regarding the therapy plan or prevention should be based on a comprehensive assessment of the patient's health condition, and the results of the genetic test should be only one of the factors supporting the decision-making process.

Collection of material

Genetic tests are performed using the material from cheek swabs. Its results depend mainly on the quality and quantity of DNA in the collected sample. The rules of collection must be strictly observed and the instructions included in the unassisted material collection kit must be followed.

Irrespective of the observance of laboratory standards, the isolated material may not be in sufficient quantity or may degrade (become damaged), rendering the performance of the ordered genetic test impossible. In such a case, the material may need to be collected again (a swab from the mucous membrane on the inside of the cheek). In such a case, please contact Customer Service to receive a supplementary material collection kit free of charge.